PORTFOLIO’S
COMPANIES
InSilicoTrials is an emerging startup founded by a team of life science, cybersecurity and digital innovation experts, which aims to revolutionize Healthcare through an innovative digital simulation platform. We specialize in leveraging AI and simulations to enhance drug development. Using in silico techniques, we analyze data to predict safety and efficacy of potential compounds, aiding Pharma, biotech companies, and researchers in efficient, cost-effective R&D advancement by minimizing extensive clinical trials. InSilicoTrials’ cloud-based platform offers advanced tools for in silico trials analyses, facilitating the integration of AI and simulation technology into drug development workflows.
INTA, a spinoff of the Scuola Normale Superiore (University of Pisa) and National Research Council of Italy (CNR-NANO), specializes in developing portable, multiplexed, rapid, and cost-effective biosensing systems, primarily focusing on diagnosing mild traumatic brain injuries (TBI). Founded on deep-tech innovation from research in nanoelectronics and biotechnology, INTA’s NanoAnalyzer platform offers a unique solution by bridging the gap between high-cost, lab-based tests and low-cost, low-performance rapid tests. With more than €2.5 million raised and a solid strategy to expand its applications for TBI and other pathologies or areas such as environmental monitoring and food safety, INTA is poised for significant growth in the biosensor market.
PhotonPath is pioneering the future of integrated photonics, delivering high-performance solutions that transform data acquisition, transmission, and processing capabilities across multiple industries. By leveraging their unique photonic integrated circuits (PICs), PhotonPath offers scalable, cost-effective alternatives to traditional optical systems, which are often bulky and inefficient. Their cutting-edge technology supports a wide range of applications, from telecommunications to automotive and industrial sensing, providing critical advantages in terms of speed, reliability, and environmental sustainability. With a robust product portfolio that includes the innovative interrogators for automotive applications and ultra compact and high capacity solutions for the telecommunications sector, PhotonPath is setting new standards in the photonics field, enabling faster, more reliable data handling in an increasingly digital world.
Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Founded by a team with 20 years of experience in imaging technologies, they are revolutionizing microscopy with their flagship product, PRISM – Photon-Resolved Image Scanning Microscope. This groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. PRISM’s plug-and-play design ensures seamless integration with existing microscope systems, significantly reducing costs and complexity. By democratizing access to super-resolution microscopy, Genoa Instruments empowers researchers of all sizes and budgets, unlocking groundbreaking scientific discoveries. Their mission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.
AIKO develops advanced AI-based software solutions for the space industry, designed to make satellites more autonomous and reduce reliance on human intervention. Tailored for a range of mission scenarios—including Earth observation, telecommunications, in-orbit servicing, and deep space exploration—AIKO’s software enhances automation in key areas including payload data processing, platform data analysis, and distributed tasking and mission planning. AIKO’s software is highly adaptable, seamlessly integrating with existing infrastructure, and can be deployed both on satellites and within mission control centers, requiring minimal customization across various mission types.
Fluid Wire Robotics (FWR) is redefining how robots are built and deployed in the most challenging environments. FWR is a deep tech startup that has developed the world’s first robotic technology capable of operating in any extreme setting, including radioactive zones, high temperatures, explosive environments, underwater depths, and the vacuum of space. Adapting conventional robots for hostile environments results in complex, costly designs with limited scalability. FWR solves this by reinventing robotic design, making robots naturally suitable for any harsh environment. By leveraging its proprietary technology, FWR’s fully electric manipulators deliver unparalleled reliability, safety, and performance in harsh conditions.
AI4IV operates at the intersection of artificial intelligence, neuromorphism, and advanced sensor technology, with the aim of creating a new generation of smart devices for industry, automotive, space, robotics, precision agriculture, and urban infrastructure. The technological heart of the startup is FlyEye, a newly designed neuromorphic sensor that emulates the functioning of human neurons, ensuring real-time recognition of objects in the environment even in extreme lighting conditions, overcoming the limitations of conventional sensors that are subject to overexposure or underexposure. With its technology and bio-inspired approach, AI4IV is overcoming the limitations of current computer vision solutions, offering a true ‘artificial eye’ that almost perfectly mimics the functioning of the ‘brain-eye’ system in humans.
Random Power is an innovative deep-tech startup specializing in the development of Quantum Random Number Generators (QRNGs), leveraging proprietary semiconductor-based technology to generate true quantum entropy for advanced cryptographic and security applications. Originating from research conducted at the University of Insubria and AGH University of Science and Technology, and building on expertise in silicon detectors developed for CERN experiments, Random Power exploits the quantum tunneling effect to produce intrinsically unpredictable random numbers. The company offers a vertically integrated portfolio of solutions, ranging from high-performance hardware systems for data centers and secure communications to compact ASIC-based chips designed for embedded systems, IoT devices, and digital identity infrastructures. By enabling scalable, cost-effective, and easily integrable quantum entropy generation, Random Power addresses critical needs in cybersecurity, telecommunications, and high-performance computing, positioning itself as a key player in the emerging market of quantum-safe security technologies.
K3RX is an innovative Italian startup and CNR spin-off developing ultra-high-temperature carbon-ceramic composite components engineered to withstand extreme heat, wear, and oxidation in the most demanding operating environments. Leveraging proprietary technologies and exclusive licensed IP derived from advanced materials research, K3RX produces highly customizable components capable of operating above 2,000°C, with performance reaching up to 2,700°C. Its solutions are designed for high-value applications across aerospace, defense, automotive, and energy, where lightweight, durable, and high-performance materials are critical to improving system reliability, safety, and efficiency. By combining superior thermal and mechanical resistance with strong customization capabilities through an engineer-to-order model, K3RX positions itself as a key enabling technology player in advanced manufacturing, addressing the growing demand for next-generation materials in strategic industrial sectors.
OhmSpace is an innovative SpaceTech startup specializing in advanced electric propulsion systems for small satellites and space constellations. Founded in 2021, the company develops high-performance resistojet-based propulsion solutions designed to improve efficiency, sustainability, and operational flexibility in space missions. Its flagship product, STAR-Water-nano, leverages a patented high-temperature electrothermal technology using water as a non-toxic propellant, enabling up to 70% higher efficiency and significant reductions in fuel consumption and operational costs compared to traditional chemical and electric propulsion systems. Designed for CubeSats and microsatellites operating in LEO and GEO orbits, the system offers scalable, cost-effective, and easily integrable propulsion capabilities. By combining proprietary technology, additive manufacturing processes, and a sustainable approach to space propulsion, OhmSpace is positioning itself as a key player in the rapidly growing satellite propulsion market, addressing the increasing demand for safer, more efficient, and environmentally responsible space infrastructure.
UpSurgeOn is an Italian MedTech startup specialized in advanced surgical training through hyper-realistic physical simulators integrated with augmented and virtual reality technologies. Founded in 2017 by a multidisciplinary team of neurosurgeons, engineers, and digital experts, the company aims to standardize surgical education globally by enabling accessible, high-fidelity, and cadaver-free training. Its modular ecosystem combines anatomical simulators, AR-enabled digital content, and surgical navigation tools, allowing practitioners to replicate complex procedures with high precision across multiple disciplines. Building on this foundation, UpSurgeOn is developing the MetaPhysical Hub, a next-generation platform integrating AI-driven coaching, sensorized simulators, and patient-specific simulations, enabling quantitative performance assessment and personalized training. With operations in over 99 countries and collaborations with more than 300 institutions and 200 MedTech companies, UpSurgeOn is positioned at the intersection of medical simulation and digital health, addressing the growing demand for scalable and data-driven surgical training solutions.
Gyala is an Italian cybersecurity company developing advanced software solutions to protect complex and mission-critical IT, OT, and IoT environments. Founded by a team with deep experience in defense, systems engineering, and cyber intelligence, Gyala leverages proprietary technology originally developed through military R&D programs and later adapted for commercial applications. Its core platform, Agger, combines threat detection and automated response, distributed edge intelligence, legacy-device compatibility, and integrated compliance capabilities into a unified all-in-one architecture. Designed for sectors such as defense, healthcare, energy, industry, finance, and public administration, Gyala positions itself as an end-to-end cybersecurity provider, combining software and professional services to strengthen digital resilience across critical infrastructures. With its “100% Italian” technology stack and strong focus on cyber sovereignty, regulatory alignment, and IT/OT convergence, Gyala is emerging as a differentiated player in the European cybersecurity landscape.
